Penicillin Fermentation

In September 1928, Alexander Fleming, a professor of bacteriology at St. Mary's Medical School in London, observed that mould had developed accidentally on a Staphylococcus aureus culture plate that was left on the laboratory bench and that the mould had created a bacteria-free circle around itself. He was inspired to further experiment and he found that a mould culture prevented growth of Staphylococcus, even when diluted 800 times. He named the active substance penicillin [154], In December 1945, he and his colleagues (Florey and Chain) received the Nobel Price in medicine for the discovery of penicillin and its curative effect in various infectious diseases [424]. This accidental discovery saved thousands of lives in later years and had a major impact on pharmaceutical production of various antibiotics.

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