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Figure 1. Comparison of the primary structures of the aldehyde reductase from S. salmonicolor and aldo-keto reductase superfamily proteins. The sequences of the aldehyde reductase (sALR), human aldehyde reductase (hALR), human aldose reductase (hADR), rat aldose reductase (rADR), bovine prostaglandin F synthase (bPGF), frog p-crystallin (fRHO), the yeast nuclear gene product (sGCY), and 2,5-diketogluconic acid reductase from Corynebacterium sp. (cDKG) are aligned. Gaps in the aligned sequences are indicated (-). Identical amino acid residues are enclosed in boxes. See Ref. 38 for details.

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