Scheme 6.

PheOMe proceeds spontaneously. Fumaric-PheOMe was reportedly produced in good yield by isomerization ofMPM (40). Unfortunately, the yield at the step of ammonia addition is too low to be applicable in an industrial APM production process. A new microbial strain exhibiting higher lyase activity has recently been reported by Xu et al. (43), but even with this strain, productivity seems to be insufficient. Further screening of bacteria and improvement of ammonia lyase thus appears to be important.

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Brew Your Own Beer

Brew Your Own Beer

Discover How To Become Your Own Brew Master, With Brew Your Own Beer. It takes more than a recipe to make a great beer. Just using the right ingredients doesn't mean your beer will taste like it was meant to. Most of the time it’s the way a beer is made and served that makes it either an exceptional beer or one that gets dumped into the nearest flower pot.

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