ATP production was also influenced differently from ammonia addition (increasing ATP production) and from lowering external pH (decreasing ATP production). Miller et al. (52) observed an increase in glucose consumption rate as a result of ammonia addition, although the decrease in extracellular pH led to a decrease in glucose consumption rate. Thus, it can be concluded that the mechanisms of the ammonia effects may not be as simple as they were originally thought to be. The alteration of intracellular pH by ammonia cannot alone explain the observations.
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