Metabolism

L-glutamic acid is split into a-ketoglutaric acid and ammonia by glutamate dehydrogenase. By the reverse reac tion, L-glutamic acid is synthesized from a-ketoglutaric acid, a member of the tricarboxylic acid (TCA) cycle of glycolysis. Whereas glutamate transaminase is nonspecific for the pairs of keto acids and amino acids, L-glutamate is the only amino acid in mammalian tissues that undergoes oxidative deamination at an appropriable rate. The formation of ammonia from a-amino groups requires their conversion to the a-amino nitrogen of L-glutamate. Thus, L-glutamic acid is a key substance in the nitrogen metabolism of amino acids. Glutamate dehydrogenase is widely distributed in microorganisms and higher plants as a catalyst in the synthesis of L-glutamic acid from a-ketoglutaric acid and free ammonia. Transaminase is contained in a wide variety of microorganisms.

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Brew Your Own Beer

Discover How To Become Your Own Brew Master, With Brew Your Own Beer. It takes more than a recipe to make a great beer. Just using the right ingredients doesn't mean your beer will taste like it was meant to. Most of the time it’s the way a beer is made and served that makes it either an exceptional beer or one that gets dumped into the nearest flower pot.

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