Immune System Boosters

Immunity Crisis

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Immunity Crisis Summary

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Production Methods of Carbohydratebased Therapeutics

Polysaccharide based therapeutics such as lentinan, schizophyllan and Hib polysaccharide are mainly produced by fermentation due to die limitation of current technology of chemical or enzymatic methods in synthesizing large size of carbohydrates automatically. Since Hib vaccine is a type of bacterial capsular polysaccharide, which is type II T-cell independent antigen and is poorly immunogenic in children under 2 years of age. However, young children are the most susceptible to bacterial infections. Thus, Hib polysaccharide-protein conjugate vaccine is developed to convert the immune response to a T-cell dependent response, which can induce immunological memory and is immunogenic in very young child (77).

Polyclonal Antibodies

The first is related to the method of production. Poly-clonal antibodies are produced naturally, by the immune response of an immunized animal. The antibody is purified from serum, with the necessity of removing all the serum impurities, including host antibodies. Monoclonal antibodies, however, are produced in incubators. Historically, for small batches, the incubator has been a mouse, with the resulting ascites fluid containing the desired antibody. This ascites fluid is related to serum and can be an equally

Therapeutic Properties Of Liquid Fermented Milk Products

Much has been written about studies on the therapeutic value of fermented milks involving in vitro, animal, and human studies. Various benefits have been suggested, including the reduction in risk of gastrointestinal illnesses such as diarrhea, improved lactose digestion, enhancement of the immune function, decreasing Helicobacter pylori infection, reduction of cholesterol and certain allergies, anticarcinogenic action and so forth (49,50). As a result of this, commercial fermented milks with health claims have been developed in some countries and in Japan the Ministry for Welfare developed FOSHU (Foods for Specified Health Use) regulations in 1993 for such products (51). Some lactic acid bacteria have been shown to stimulate immune functions by activating macrophages, increasing the levels of cytokines, and increasing immunoglobulin levels (especially those of IgA). Organisms identified in such functions include Lactobacillus johnsonii LA1, Lactobacillus GG, and Lactobacillus casei...

Presence Absence of Receptor Ligand Interactions

The presence of receptor-ligand interactions can also lead to the induction of apoptosis. For instance, in the Fas-FasL system, binding of the Fas ligand to the Fas receptor can trigger apoptosis (19). This mechanism is responsible for the regulation of the immune system. Autoreactive B cells undergoing maturation (20) and autoreactive mature T cells (21) are eliminated by the Fas-mediated induction of apoptosis. Fas also acts as the off' switch for the immune system by inducing apoptosis in antigen-activated B and T cells (22). Molecular dissection of the Fas-FasL system has provided important insights into the early stages of the signaling cascade that leads to the expression of the death pathway (see Genetics of Apoptosis ).

Probiotic Features of Starter Cultures

Probiotics are live microbial food supplements that benefit the health of consumers by maintaining or improving their intestinal microbial balance (88). Species of Lactobacillus and Streptococcus have traditionally been used in fluid fermented dairy products to promote human health (89). These probiotic starters may influence the microbial ecology of the host, lactose intolerance, incidence of diarrhea, mucosal immune response, levels of cholesterol, and cancer. Besides the traditional carrier of probiotics, which is yogurt, the market share of probiotic drinks is expanding rapidly. The most common probiotic strains are lactobacilli. A number of them are now being successfully commercialized, such as Lactobacillus rhamnosus GG (90). Lb. casei Shirota (91) and L. acidophilus LA-1 (92). The scientific basis of these strains in relation to their proposed positive effects on the human health is quite extensive however, most of the evidence is obtained from diseased human populations....

Safety

Bacillus species have been used extensively in the fermentation industry for the production of a range of products including enzymes, fine biochemicals, antibiotics, and insecticides. In addition, a strain of B. subtilis is used for the fermentation of soybeans to Natto, an extensively consumed ( 108 kg annum) traditional Japanese food product. In a review of the safety of B. subtilis and B. amylo-liquefaciens (these strains were considered to be synonymous up to 1973 100 ), no reports were found of infection or toxicity relating to B. amyloliquefaciens. In the case of B. subtilis, the situation was complicated by the fact that before about 1970 diagnostic laboratories did not distinguish between B. cereus and B. subtilis. Virtually all reports of putative B. subtilis infections since that time either were associated with drug abuse or occurred in patients whose immune system had been compromised by treatment with immunosuppressants or chemotherapeutic agents. This low incidence of...

How To Bolster Your Immune System

How To Bolster Your Immune System

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