Minerals

concentration of the nitrogen source in the culture medium (Aharonowitz, 1980). Antibiotic production may be inhibited by a rapidly utilized nitrogen source (NH4, N03 , certain amino acids). The antibiotic production only begins to increase in the culture broth after most of the nitrogen source has been consumed.

All micro-organisms require certain mineral elements for growth and metabolism (Hughes and Poole, 1989, 1991). In many media, magnesium, phosphorus, potassium, sulphur, calcium and chlorine are essential components, and because of the concentrations required, they must be added as distinct components. Others such as cobalt, copper, iron, manganese, molyb

Table 4.9. Best nitrogen sources for some secondary metabolites

Product Main nitrogen source(s) Reference

Product Main nitrogen source(s) Reference

Table 4.9. Best nitrogen sources for some secondary metabolites

Penicillin

Corn-steep liquor

Moyer and Coghill (1946)

Bacitracin

Peanut granules

Inskeep etal. (1951)

Riboflavin

Pancreatic digest of gelatine

Malzahn et al. (1959)

Novobiocin

Distillers' solubles

Hoeksema and Smith (1961)

Rifomycin

Pharmamedia

Sensi and Thiemann (1967)

Vinegar For Your Health

Vinegar For Your Health

A resource for the many ways you can use Vinegar to improve your health! In today's society of miracle medicine, we often overlook things that have been around hundreds of years! Things like Vinegar!

Get My Free Ebook


Post a comment