Further Reading

Selected examples from the SSF literature in which models are developed that describe the various heat and mass transfer phenomena described in this chapter. These models therefore contain terms similar to those shown in this chapter Mitchell DA, von Meien OF (2000) Mathematical modeling as a tool to investigate the design and operation of the Zymotis packed-bed bioreactor for solid-state fermentation. Biotechnol Bioeng 68:127-135 Mitchell DA, Tongta A, Stuart DM, Krieger N (2002) The potential for establishment of axial temperature profiles during solid-state fermentation in rotating drum bioreactors. Biotechnol Bioeng 80:114-122 Oostra J, Tramper J, Rinzema A (2000) Model-based bioreactor selection for large-scale solid-state cultivation of Coniothyrium minitans spores on oats. Enz Microbial Technol 27:652-663

Rajagopalan S, Modak JM (1994) Heat and mass transfer simulation studies for solid-state fermentation processes. Chem Eng Sci 49:2187-2193 Saucedo-CastaƱeda G, Gutierrez-Rojas M, Bacquet G, Raimbault M, Viniegra-Gonzalez G (1990) Heat transfer simulation in solid substrate fermentation. Biotechnol Bioeng 35:802-808

Stuart DM, Mitchell DA (2003) Mathematical model of heat transfer during solid-state fermentation in well-mixed rotating drum bioreactors. J Chem Technol Biotechnol 78:1180-1192

Weber FJ, Oostra J, Tramper J, Rinzema A (2002) Validation of a model for process development and scale-up of packed-bed solid-state bioreactors. Biotechnol Bioeng 77:381393

Basic and easy to read introductions to the modeling of heat and mass transfer in bioprocessing

Van Den Akker HEA, Heijnen JJ, Leach CK, Mudde RF (1992) Bioprocess Technology, Modelling and Transport Phenomena. Butterworth Heinemann, Oxford.

Johnson AT (1998) Biological process engineering: an analogical approach to fluid flow, heat transfer, and mass transfer applied to biological systems. John Wiley & Sons, New York.

Introductions to heat and mass transfer phenomena (not in the context of biopro-


Thomson WJ (2000) Introduction to transport phenomena. Prentice Hall, Upper Saddle River

Brodkey RS, Hershey HC (2003) Transport Phenomena: A Unified Approach, vols. 1 and 2. Brodkey Publishing, Columbus, Ohio

Overview of approaches to modeling heat and mass transfer in SSF bioreactors

Mitchell DA, von Meien OF, Krieger N (2003) Recent developments in modeling of solidstate fermentation: heat and mass transfer in bioreactors. Biochem Eng J 13:137-147

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