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bed height (cm)

Fig. 7.7. Temporal and spatial temperature gradients in packed-bed bioreactors. (a) Temporal temperature profiles at different axial positions in the 50-cm-high packed-bed bioreactor of Weber at al. (2002), for growth of Coniothyrium minitans on hemp impregnated with nutrients. The numbers above each curve represent the cm height in the bed at which the temperature was measured. Adapted from Weber et al. (2002) with kind permission from John Wiley & Sons, Inc. (b) Off-gas relative humidity for fermentations undertaken with Coniothyrium minitans and Aspergillus oryzae. Adapted from Weber et al. (2002) with kind permission from John Wiley & Sons, Inc. (c) Temporal temperature profiles, at a bed height of 17 cm, in the 35-cm-high packed-bed bioreactor of Ghildyal et al. (1994), during the growth of Aspergillus niger on wheat bran. Adapted from Ghildyal et al. (1994) with kind permission of Elsevier. (d) Effect of air flow rate and bed height on the maximum temperature experienced during the cultivation. Adapted from Ghildyal et al. (1994), with kind permission of Elsevier

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