Where Continuously Agitated Forcefully Aerated Bioreactors Have Been Used

Of course, bioreactors that are designed for continuous mixing can also be used in the intermittent-mixing mode. However, there is a difference: If a bed is to remain static for long periods, then it is important to design the aeration system to aerate the bed evenly during the static periods. Uniform distribution of the air may not be so crucial for a continuously mixed bioreactor, since the continuous mixing action should bring all parts of the bed to the well-aerated zone. Bioreactors that have been used in the intermittently mixed mode of operation will be mentioned here if they can also be operated effectively in the continuously mixed mode.

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